個人簡介
研究領(lǐng)域和方向
物理有機化學(xué):主客體識別機制以及構(gòu)象對化學(xué)反應(yīng)途徑的調(diào)控
生物物理化學(xué):利用分子模擬、深度學(xué)習(xí)、光譜和波譜技術(shù)研究生物大分子與生物大分子、小分子的動態(tài)識別機制和結(jié)構(gòu)調(diào)控
教育背景
1993-1997 遼寧大學(xué)化學(xué)系本科生, 理學(xué)學(xué)士學(xué)位;
1997-2000 遼寧大學(xué)化學(xué)系所碩士研究生, 理學(xué)碩士學(xué)位;
2000-2003 中科院化學(xué)所博士研究生, 理學(xué)博士學(xué)位
工作履歷
2000-2002 比利時魯汶大學(xué)化學(xué)系,博士后
2002-2003 瑞典厄勒布魯生命科學(xué)中心,博士后人
研究成果
Dynamics of 5R-Tg Base Flipping in DNA Duplexes Based on Simulations-Agreement with Experiments and Beyond Wang,SD;Eriksson, L A* and?Zhang,RB* JOURNAL OF CHEMICAL INFORMATION AND MODELING 2022,62,386-398
Markov state models elucidate the stability of DNA influenced by the chiral 5S-Tg base Wang,SD; Zhang,RB* and?Eriksson, LA* NUCLEIC ACIDS RESEARCH 2022,50,9072-9082
Off-On Squalene Epoxidase-Specific Fluorescent Probe for Fast Imaging in Living Cells Zang, Tienan;?Wang, SD;Su, S;Gao, MX;Chen, QQ;Liang, CL;Jing, J;Zhang, RB*;Zhang, XL*ANALYTICAL CHEMISTRY 2021, 93,14716-14721
Molecular dynamics study of the recognition of ATP by nucleic acid aptamers Xie, Ya-chen; Eriksson, Leif A. *; Zhang, Rubo* NUCLEIC ACIDS RESEARCH,2020,48(12),6471-6480
Oxygen Dependent Purine Lesions in Double-Stranded Oligodeoxynucleotides: Kinetic and Computational Studies Highlight the Mechanism for 5 ',8-Cyclopurine Formation Chatgilialoglu, C* ; Eriksson, LA ; Krokidis, MG ; Masi, A ; Wang, SD ; Zhang, RB* JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2020,142(12),5825-5833